2006 WPI Football Schedule
Overall Record: 3-6, Liberty League Record: 0-6
| Date | Opponent | Time | Result | Links | ||
| Sep. 9 | Worcester State | 12:00 PM | W, 40-20 | Boxscore Recap | ||
| Sep. 16 | Becker College | 2:00 PM | W, 52-16 | Boxscore Recap | ||
| Sep. 23 | US Merchand Marine Academy * | 6:00 PM | L, 33-14 | Boxscore Recap | ||
| Sep. 30 | at Hobart College * | 1:00 PM | L, 19-14 | Boxscore Recap | ||
| Oct. 7 | Union College * | 1:00 PM | L, 28-27 | Boxscore Recap | ||
| Homecoming | ||||||
| Oct. 21 | University of Rochester * | 12:00 PM | L, 34-7 | Boxscore Recap | ||
| Oct. 28 | at Rensselaer * | 1:00 PM | L, 26-0 | Boxscore Recap | ||
| Nov. 4 | at Mount Ida College | 1:00 PM | W, 46-20 | Boxscore Recap | ||
| Nov. 11 | St. Lawrence University * | 12:00 PM | L, 31-7 | Boxscore Recap | ||
| Home games in bold * = Liberty League game | ||||||